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What is naproxen? Naproxen sodium or INN is described as a non-steroidal anti-inflammatory drug or NSAID which is principally used to alleviate mild to moderate pain, fever, inflammation and stiffness brought on by conditions including osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and the treatment of primary dysmenorrhea. It functions by inhibiting both the COX-1 and COX-2 enzymes. Naproxen and naproxen sodium are marketed and sold under several trade names which are inclusive of Aleve, Anaprox, Antalgin, Feminax Ultra, Flanax, Inza, Miranax, Naprelan, Naprogesic, Naprosyn, Narocin, Proxen, Synflex and Xenobid.

What is Naproxen

Naproxen was, in its beginning phases, marketed as the prescription drug Naprosyn in the year 1976, and naproxen sodium was initially marketed under the trade name Anaprox in 1980. It is still sold as a prescription-only drug in many places across the globe. The U.S. Food and Drug Administration, or FDA for short, approved the use of naproxen sodium as an over-the-counter medication in 1994. Over the counter preparations are sold under the trade name Aleve. In Australia, packets of 275 mg tablets of naproxen sodium are categorized as Schedule 2 Pharmacy Medicines, with a maximum daily dosage of 5 tablets/1375 mg. In the United Kingdom, 250 mg tablets of naproxen were approved for over the counter sale under the brand name Feminax Ultra in 2008, for the treatment of primary dysmenorrhoea in women between the ages of 15 to 50. Aleve became available over-the-counter in many provinces in Canada on July 14, 2009 excluding British Columbia, Quebec, Newfoundland and Labrador.

Naproxen is a constituent of the 2-arylpropionic acid (profen) family of NSAIDs. The base acid is an odorless, white to off-white crystalline substance. It is lipid-soluble and mostly insoluble in water. It has a melting point of 153 °C.

IP110 Naproxen Tablets: Like other NSAIDs, naproxen can obstruct the excretion of sodium and lithium. People who take lithium supplements must be extremely careful when taking Naproxen. Naproxen is also not ideal for use with NSAIDs of the salicylate family (Aspirin) both drugs may possibly reduce each other's effectiveness or along with anticoagulants which may increase risk of bleeding. Naproxen preparations that contain sodium e.g., Anaprox, Aleve, etc. are not generally administered to patients with sodium-sensitive hypertension, as a result of a potential adverse effect on blood pressure in this small group of hypertensive patients.

In August 2006, the Journal Birth Defects Research Part B published results that demonstrated that pregnant women who take NSAIDs including naproxen in the first trimester of pregnancy run an elevated risk of having a child with some form of congenital birth defects, specifically heart abnormalities.

Now you know the answer to your question, "What is naproxen?"